(A) How do the different actors in your ecosystems (university, hospitals, start-ups, industry, institutions) coordinate/interact to generate innovation in the medical field and work together to valorise these innovations (start up creation, technology transfer etc)?

In my organisation I am in charge of identifying the best national and international partners to help structure the health ecosystem of New Aquitaine. My objective is, among other things, to identify good practices in other ecosystems and draw inspiration from them to help the various players in the region in their development choices.

(B) How do the different actors in your ecosystems (university, hospitals, start-ups, industry, institutions) coordinate/interact to generate innovation in the medical field and work together to valorise these innovations (start up creation, technology transfer etc)?

In my organisation I am in charge of identifying the best national and international partners to help structure the health ecosystem of New Aquitaine. My objective is, among other things, to identify good practices in other ecosystems and draw inspiration from them to help the various players in the region in their development choices.

Which biomarkers would be representative and relevant in the tear fluid?

Azalea Vision is a medical device company focused on smart contact lenses to treat ocular conditions (e.g. iris disorders). The electronics from our smart contact lens can be adapted to accomodate other applications. We are especially interested in integrating sensing capabilities in our platform, but we need to gain insights into the relevant biomarkers in the tear fluid to develop a product that would be first, viable, and second, feasible.

Looking for a method or algorithm to detect differences in cancer patients (patient baseline characteristics, images (CT/MRI/PET & other scans), biomarkers, genes, that correlate predictability of patient outcome in lung, prostate, and brain cancer for therapies applied

Cancer imaging is extensively available for initial diagnosis and then followup post therapy (chemo/radiation). Bionmarkers and genetic markers are also measured for patients. Use of AI to interpret this data could yield a valuable diagnostic/prognostic tool and also aid in tailoring therapies for particular patients for optimum outcomes. in addition it could act a a powerful outcome measurement tool potentially identifying and/or validating therapies earlier

(A) How do we bring digital tools to the monitoring and evaluation of community health initiatives in a way that is efficient, accurate and user-friendly, including in settings where time is tight, resources are scarce and internet access is poor.

Croí and many other community organisations and community based health and social care service providers are routinely delivering carefully developed programmes and initiatives to a wide variety of populations in settings such as home, community and health centres. All service providers and managers are highly motivated to collect data to ensure activities are effective in terms of impact and resource use. In the area of cardiovascular disease prevention in the west of Ireland a group of stakeholders is seeking to develop a way to standardise our approach to data collection and collate the data gathered through our ongoing activities, to develop a large dataset of west of Ireland data that we can draw from influence national policy making. Challenges include agreeing a core outcome set, developing a data collection form and tool suitable for our settings, ensuring GDPR compliance, storage and sharing.

(B) How do we bring digital tools to the monitoring and evaluation of community health initiatives in a way that is efficient, accurate and user-friendly, including in settings where time is tight, resources are scarce and internet access is poor.

Croí and many other community organisations and community based health and social care service providers are routinely delivering carefully developed programmes and initiatives to a wide variety of populations in settings such as home, community and health centres. All service providers and managers are highly motivated to collect data to ensure activities are effective in terms of impact and resource use. In the area of cardiovascular disease prevention in the west of Ireland a group of stakeholders is seeking to develop a way to standardise our approach to data collection and collate the data gathered through our ongoing activities, to develop a large dataset of west of Ireland data that we can draw from influence national policy making. Challenges include agreeing a core outcome set, developing a data collection form and tool suitable for our settings, ensuring GDPR compliance, storage and sharing.

(A) How can we advance data collection in healthcare and from citizens/patients and make it accessible to improve patient outcomes in the longer term?

In a national or European perspective increased use of digital health data is essential to leverage future medical research, new and innovative therapeutics and medtech products and for a modern health care system. Data collection in healthcare allows health systems based on, for example AI-tech, to create holistic views of patients, personalize treatments, advance treatment methods, improve communication between doctors and patients, and enhance health outcomes. How can we set up systems that will make the best use of these opportunities? And how can the patient journey be included?

(B) How can we advance data collection in healthcare and from citizens/patients and make it accessible to improve patient outcomes in the longer term?

In a national or European perspective increased use of digital health data is essential to leverage future medical research, new and innovative therapeutics and medtech products and for a modern health care system. Data collection in healthcare allows health systems based on, for example AI-tech, to create holistic views of patients, personalize treatments, advance treatment methods, improve communication between doctors and patients, and enhance health outcomes. How can we set up systems that will make the best use of these opportunities? And how can the patient journey be included?

What is the effects of different compression therapy regimens on physiological and pathological parameters (e.g. those relevant to venous insufficiency or venous leg ulcers)?

We have developed a wearable pressure sensing device and digital platform for monitoring compression therapy, the cornerstone treatment for venous leg ulcers. We are looking to refine standards of care through data-driven, evidence-based innovation.

How can we motivate people to change their lifestyle using combination of genetics and a diet app? How are the most effective strategies for reducing Type 2 Diabetes and other lifestyle disease risks risk using genetics and diet app?

Developers of genetic tests based on polygenic risk scores (PRS) technology (detecting lactose- and gluten intolerance, measuring genetic predisposition to obesity, type 2 diabetes)

What can we do so that AI solutions and doctors work together to improve the delivery of care?

Legit.Health is a medical device manufacturer that develops clinical artificial intelligence to help general practitioners in the process of referral. Legit.Health also provides computer vision algorithms that HCPs can use to measure the effectiveness of treatments and monitor patients remotely. The end goal of the company is to improve the reliability of healthcare providers and patient’s health outcomes and their autonomy and control.

How can a tactile breathing device such as moonbird be used to help relieve symptoms of tinnitus?

Slow breathing exercises regulate the autonomic nervous system, which is involved in the body’s stress response. It improves overall physical and emotional well-being, including feelings of anxiety, and can therefore reduce tinnitus symptoms. Slow breathing also promotes relaxation and improve sleep quality, which may be especially helpful for individuals with tinnitus who experience sleep disturbances as a result of their symptoms. In addition, slow breathing increases blood flow and oxygenation to the body, including the auditory system. This may improve overall ear health and reduce tinnitus symptoms. Moonbird is a tactile breathing device designed to guide users in doing slow breathing exercises in an intuitive and effortless way. It is created to help people relax and fall asleep. However, given the possible benefits of breathing exercises for tinnitus, we believe that moonbird could be used in the treatment of tinnitus as well. Yet, the question remains how.

How improve the engagement and motivation of people who have lost the use of their limb in a personalised rehabilitation process ?

Myotact is a French start-up created in 2022 after 4 years of research at the Institute of Cognitive and Integrative Neurosciences of the University of Bordeaux to restore mobility and improve the rehabilitation of people who have lost the use of their limbs.

How can we set up in-silico trials/validations for imaging software?

Validation of post-processing software for medical imaging is challenging due to data access (input or output) and/or ground truth definition. In-silico trials could help designing a controlled environments where all these information are known. What could be the validity of these trials and how to design them especially for post processing imaging software extracting measurements and/or biomechanical indicators.

Are there any Neurological diseases which could benefit from eye movement quantification where today standard eye examinations are made?

We use an Eyetracker camera from Tobii to record Eye movements for the purpose of investigating anomalies in eye-movements in patients with Parkinsons, looking at Smooth pursuit, fixations and saccades.

As a start up developing a remote monitoring platform within the palliative care space – how do we validate that the patient-facing component (smartphone app) is as intuitive and user-friendly for an older population?

SymPhysis Medical are developing a catheter-based drainage solution to help patients with terminal cancers to drain fluid that builds up in the chest (condition known as malignant pleural effusion) to relieve them of symptoms such as chest pain and breathlessness. In conjunction with the drainage device SymPhysis Medical will provide hospitals with a remote monitoring platform that aims to reduce unnecessary hospital visits for patients during their end-of-life stage. One aspect of the monitoring platform is a patient app that will coach patients and allow them to track treatment progress. As patient with this condition, are typically 65 years old or older, we want to ensure the app is as intuitive and user-friendly as possible for this patient population and not a burden.

(A) How could data collected as a part of caring for patients at home be harmonized across regions?

The home-care sector is growing across Europe. To facilitate data collection, some form of harmonization would be useful. The idea would be to be able to pool data from different regions to analyse it with regards to patient safety risks, cost benefits, treatment outcomes etc.

(B) How could data collected as a part of caring for patients at home be harmonized across regions?

The home-care sector is growing across Europe. To facilitate data collection, some form of harmonization would be useful. The idea would be to be able to pool data from different regions to analyse it with regards to patient safety risks, cost benefits, treatment outcomes etc.